Article
Microsatellite genotyping reveals a signature in breast cancer exomes.
Breast cancer research and treatment - 1 Jun 2014
McIver L J, Fonville N C, Karunasena E, Garner H R
Abstract excerpt
Genomic instability at microsatellite loci is a hallmark of many cancers, including breast cancer. However, much of the genomic variation and many of the hereditary components responsible for breast cancer remain undetected. We hypothesized that variation at microsatellites could provide additional genomic markers for breast cancer risk assessment. A total of 1,345 germline and tumor DNA samples from individuals...
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