Article
Utility of temporal artery biopsy samples for genome-wide analysis of giant cell arteritis.
Genes and immunity - 1 Jan 2000
Cremin K, Leo P, Harris J E, De Smit E, Bradbury L, McKelvie P, Hill C L, Brown M A, Hewitt A W
Abstract excerpt
Giant Cell Arteritis (GCA) is the most common vasculitis affecting the elderly. Archived formalin-fixed paraffin-embedded (FFPE) temporal artery biopsy (TAB) specimens potentially represent a valuable resource for large-scale genetic analysis of this disease. FFPE TAB samples were obtained from 12 patients with GCA. Extracted TAB DNA was assessed by real time PCR before restoration using the Illumina HD FFPE...
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