Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Use of high-plex data provides novel insights into the temporal artery processes of giant cell arteritis

6 Sept 2023

Abstract excerpt

Objective: spatial profiling of molecules involved in the temporal arteries of GCA patients and controls. Furthermore, we performed pharmacogenomic network analysis to identify potential treatment targets. Methods: Using human formalin-fixed paraffin-embedded temporal artery biopsy samples (GCA, n = 9; controls, n = 7), we performed a whole transcriptome analysis using the NanoString GeoMx Digital Spatial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis and Cardiovascular Diseases
Share to Single-cell and spatial transcriptomics
Share to Vasculitis and related conditions

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37744332
DOI: 10.3389/fimmu.2023.1237986

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of high-plex data provides novel insights into the temporal artery processes of giant cell arteritisPMID 37744332Read ↗

Genes deregulated in giant cell arteritis by Nanostring nCounter gene expression profiling in temporal artery biopsiesSemantic proximity Read ↗

Genome-wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patientsSemantic proximity Read ↗

Inflammatory Cell Composition and Immune-Related microRNA Signature of Temporal Artery Biopsies From Patients With Giant Cell Arteritis.Semantic proximity Read ↗

Identification of microRNAs and their target gene networks implicated in arterial wall remodelling in giant cell arteritis.Semantic proximity Read ↗

Risk loci involved in giant cell arteritis susceptibility: a genome-wide association study.Semantic proximity Read ↗

Giant cells in temporal artery biopsies are associated with a reduced risk of large vessel involvement in patients with giant cell arteritis : a retrospective cohort studySemantic proximity Read ↗

DNA methylation analysis of the temporal artery microenvironment in giant cell arteritisSemantic proximity Read ↗

MicroRNA markers of inflammation and remodelling in temporal arteries from patients with giant cell arteritisSemantic proximity Read ↗

Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent Giant Cell ArteritisSemantic proximity Read ↗

Utility of temporal artery biopsy samples for genome-wide analysis of giant cell arteritis.Semantic proximity Read ↗

Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis.Semantic proximity Read ↗

Potential Key Genes for Giant Cell Arteritis Revealed Based on Single-Cell Sequencing and Mendelian Randomization Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.