Article
Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis.
BMC medical genomics - 23 Jul 2018
De Smit Elisabeth, Lukowski Samuel W, Anderson Lisa, Senabouth Anne, Dauyey Kaisar, Song Sharon, Wyse Bruce, Wheeler Lawrie, Chen Christine Y, Cao Khoa, Wong Ten Yuen Amy, Shuey Neil, Clarke Linda, Lopez Sanchez Isabel, Hung Sandy S C, Pébay Alice, Mackey David A, Brown Matthew A, Hewitt Alex W, Powell Joseph E
Abstract excerpt
BACKGROUND: Giant cell arteritis (GCA) is the most common form of vasculitis affecting elderly people. It is one of the few true ophthalmic emergencies but symptoms and signs are variable thereby making it a challenging disease to diagnose. A temporal artery biopsy is the gold standard to confirm GCA, but there are currently no specific biochemical markers to aid diagnosis. We aimed to identify a less invasive...
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