Article

Estimating overdiagnosis in giant cell arteritis diagnostic pathways using genetic data: genetic association study

2023-04-24

Abstract excerpt

<h4>Objectives</h4> Prompt diagnosis of giant cell arteritis (GCA) is important to avert visual loss. False-negative temporal artery biopsy (TAB) can occur. Without vascular imaging, GCA may be overdiagnosed in TAB-negative cases, but it is unclear how often this occurs. An unbiased test is a way to address an imperfect reference standard. We used the known Human Leukocyte Antigen (HLA) region genetic association...

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Literature Corpus work: 3356cf16-a277-5c74-a660-0ee0de173392
DOI: 10.1101/2023.04.17.23288682

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