Article

Genome-wide DNA methylation study reveals specific signatures in the affected arterial tissue of giant cell arteritis patients

2025-03-04

Abstract excerpt

<h4>Objectives</h4> Giant cell arteritis (GCA) is a large-vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. <h4>Methods</h4> DNA methylation profiling was analyzed in 79 temporal artery biopsy samples (69 patien...

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Literature Corpus work: 7323e93b-d144-5855-b724-c94832074cbb
DOI: 10.1101/2025.02.27.640503

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