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Article

Identification of microRNAs and their target gene networks implicated in arterial wall remodelling in giant cell arteritis.

Rheumatology (Oxford, England) - 1 Nov 2020

Bolha Luka, Pižem Jože, Frank-Bertoncelj Mojca, Hočevar Alojzija, Tomšič Matija, Jurčić Vesna

Abstract excerpt

OBJECTIVES: To identify dysregulated microRNAs (miRNAs) and their gene targets in temporal arteries from GCA patients, and determine their association with GCA pathogenesis and related arterial wall remodelling. METHODS: We included 93 formalin-fixed, paraffin-embedded temporal artery biopsies (TABs) from treatment-naïve patients: 54 positive and 17 negative TABs from clinically proven GCA patients, and 22...

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PMID: 32594153
DOI: 10.1093/rheumatology/keaa204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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