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Article

G×G×E for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity.

PLoS genetics - 1 Jan 2014

Zhu Chen-Tseh, Ingelmo Paul, Rand David M

Abstract excerpt

Dietary restriction (DR) is the most consistent means of extending longevity in a wide range of organisms. A growing body of literature indicates that mitochondria play an important role in longevity extension by DR, but the impact of mitochondrial genotypes on the DR process have received little attention. Mitochondrial function requires proper integration of gene products from their own genomes (mtDNA) and the...

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Identifiers

PMID: 24832080
DOI: 10.1371/journal.pgen.1004354
PMCID: PMC4022469

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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