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Article

Compatibility between mitochondrial and nuclear genomes correlates with the quantitative trait of lifespan in Caenorhabditis elegans.

Scientific reports - 25 Nov 2015

Zhu Zuobin, Lu Qing, Zeng Fangfang, Wang Junjing, Huang Shi

Abstract excerpt

Mutations in mitochondrial genome have epistatic effects on organisms depending on the nuclear background, but a role for the compatibility of mitochondrial-nuclear genomes (mit-n) in the quantitative nature of a complex trait remains unexplored. We studied a panel of recombinant inbred advanced intercrossed lines (RIAILs) of C. elegans that were established from a cross between the N2 and HW strains. We...

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PMID: 26601686
DOI: 10.1038/srep17303
PMCID: PMC4658563

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