Article

Systems biology and machine learning approaches identify metabolites that influence dietary lifespan and healthspan responses across flies and humans

2023-07-10

Abstract excerpt

<h4>Summary</h4> Dietary restriction (DR) is a potent method to enhance lifespan and healthspan, but individual responses are influenced by genetic variations. Understanding how metabolism-related genetic differences impact longevity and healthspan are unclear. To investigate this, we used metabolites as markers to reveal how different genotypes respond to diet to influence longevity and healthspan traits. We ana...

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Literature Corpus work: b4c43521-74e2-5691-ae15-84b37b286e5c
DOI: 10.1101/2023.07.09.548232

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