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Article

Dietary restriction in Drosophila is dependent on mitochondrial efficiency and constrained by pre-existing extended longevity.

Mechanisms of ageing and development - 1 Jan 2000

Soh Jung Won, Hotic Sijana, Arking Robert

Abstract excerpt

We tested the effects of dietary restriction (DR) on the standard w(1118) strain as well as on our previously described Ra and La strains and their reciprocal isogenic 'cybrid' lines containing heterologous nuclear-mitochondrial combinations. The w(1118) and Ra strains, but neither the La strains nor their 'cybrid' derivatives, are DR-inducible. The Ra and La animals are more robust than the w(1118) animals, and...

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Source

Identifiers

PMID: 17928035
DOI: 10.1016/j.mad.2007.08.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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