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Article

Simultaneous characterization of metabolic, cardiac, vascular and renal phenotypes of lean and obese SHHF rats.

PloS one - 1 Jan 2014

Youcef Gina, Olivier Arnaud, L'Huillier Clément P J, Labat Carlos, Fay Renaud, Tabcheh Lina, Toupance Simon, Rodriguez-Guéant Rosa-Maria, Bergerot Damien, Jaisser Frédéric, Lacolley Patrick, Zannad Faiez, Laurent Vallar, Pizard Anne

Abstract excerpt

Individuals with metabolic syndrome (MetS) are prone to develop heart failure (HF). However, the deleterious effects of MetS on the continuum of events leading to cardiac remodeling and subsequently to HF are not fully understood. This study characterized simultaneously MetS and cardiac, vascular and renal phenotypes in aging Spontaneously Hypertensive Heart Failure lean (SHHF(+/?) regrouping (+/+) and (+/cp)...

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Source

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Identifiers

PMID: 24831821
DOI: 10.1371/journal.pone.0096452
PMCID: PMC4022510

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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