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Article

Concomitant Obesity and Metabolic Syndrome Add to the Atrial Arrhythmogenic Phenotype in Male Hypertensive Rats.

Journal of the American Heart Association - 17 Sept 2017

Hohl Mathias, Lau Dennis H, Müller Andreas, Elliott Adrian D, Linz Benedikt, Mahajan Rajiv, Hendriks Jeroen M L, Böhm Michael, Schotten Ulrich, Sanders Prashanthan, Linz Dominik

Abstract excerpt

BACKGROUND: Besides hypertension, obesity and the metabolic syndrome have recently emerged as risk factors for atrial fibrillation. This study sought to delineate the development of an arrhythmogenic substrate for atrial fibrillation in hypertension with and without concomitant obesity and metabolic syndrome. METHODS AND RESULTS: We compared obese spontaneously hypertensive rats (SHR-obese, n=7-10) with lean...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28919580
DOI: 10.1161/JAHA.117.006717
PMCID: PMC5634308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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