Article

A matter of food and substrain: obesogenic diets induce differential severity of cardiac remodeling and diastolic dysfunction in C57Bl/6J and C57Bl/6N substrains

2024-03-17

Abstract excerpt

<h4>ABSTRACT</h4> The prevalence of metabolic syndrome in cardiac diseases such as heart failure with preserved ejection fraction (HFpEF) prompts the scientific community to investigate its adverse effects on cardiac function and remodeling and its associated mechanisms. However, the choice of a preclinical model of obesity-induced cardiac remodeling has proven more challenging with inconsistencies often found in...

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Literature Corpus work: 6ef61f38-0a18-5791-8e1c-db065f65228b
DOI: 10.1101/2024.03.15.584713

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