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Article

Hydrolytic function of Exo1 in mammalian mismatch repair.

Nucleic acids research - 1 Jun 2014

Shao Hongbing, Baitinger Celia, Soderblom Erik J, Burdett Vickers, Modrich Paul

Abstract excerpt

Genetic and biochemical studies have previously implicated exonuclease 1 (Exo1) in yeast and mammalian mismatch repair, with results suggesting that function of the protein in the reaction depends on both its hydrolytic activity and its ability to interact with other components of the repair system. However, recent analysis of an Exo1-E109K knockin mouse has concluded that Exo1 function in mammalian mismatch...

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Identifiers

PMID: 24829455
DOI: 10.1093/nar/gku420
PMCID: PMC4066806

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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