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Article

Stem cell therapy and cellular engineering for treatment of neuronal dysfunction in Huntington's disease.

Biotechnology journal - 1 Jul 2014

Choi Kyung-Ah, Hwang Insik, Park Hang-soo, Oh Seung-Ick, Kang Seongman, Hong Sunghoi

Abstract excerpt

Huntington's disease (HD) is a fatal inherited neurodegenerative disorder characterized by progressive loss of neurons in the striatum, a sub-cortical region of the forebrain. The sub-cortical region of the forebrain is associated with the control of movement and behavior, thus HD initially presents with coordination difficulty and cognitive decline. Recent reprogramming technologies, including induced...

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PMID: 24827816
DOI: 10.1002/biot.201300560

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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