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Induced pluripotent stem cells for modeling neurological disorders

1 Jan 2015

Abstract excerpt

Several diseases have been successfully modeled since the development of induced pluripotent stem cell (iPSC) technology in 2006. Since then, methods for increased reprogramming efficiency and cell culture maintenance have been optimized and many protocols for differentiating stem cell lines have been successfully developed, allowing the generation of several cellular subtypes in vitro. Gene editing technologies...

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PMID: 26722648
DOI: 10.5500/wjt.v5.i4.209

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