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Concise Review: The Use of Stem Cells for Understanding and Treating Huntington's Disease.

Stem cells (Dayton, Ohio) - 1 Feb 2018

Connor Bronwen

Abstract excerpt

Two decades ago, researchers identified that a CAG expansion mutation in the huntingtin (HTT) gene was involved in the pathogenesis of Huntington's disease (HD). However, since the identification of the HTT gene, there has been no advance in the development of therapeutic strategies to prevent or reduce the progression of HD. With the recent advances in stem cell biology and human cell reprogramming technologies,...

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Identifiers

PMID: 29178352
DOI: 10.1002/stem.2747

Genes

HTT

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