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Article

COMT gene and risk for Parkinson's disease: a systematic review and meta-analysis.

Pharmacogenetics and genomics - 1 Jul 2014

Jiménez-Jiménez Félix J, Alonso-Navarro Hortensia, García-Martín Elena, Agúndez José A G

Abstract excerpt

BACKGROUND/AIMS: Several single-nucleotide polymorphisms (SNPs) in the catechol-O-methyltransferase (COMT) gene have been associated with the risk of developing Parkinson's disease (PD). We conducted a systematic review and a meta-analysis including all the studies published on PD risk related with COMT SNPs (mainly rs4680). We also reviewed the possible relationship of COMT SNPs with clinical,...

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Source

Identifiers

PMID: 24819480
DOI: 10.1097/FPC.0000000000000056

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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