Article

Does<i>COMT</i>Play a Role in Parkinson’s Disease Susceptibility Across Diverse Ancestral Populations?

2025-04-11

Abstract excerpt

<h4>Background</h4> The catechol-O-methyltransferase ( COMT ) gene is involved in brain catecholamine metabolism, but its association with Parkinson’s disease (PD) risk remains unclear. <h4>Objective</h4> To investigate the relationship between COMT genetic variants and PD risk across diverse ancestries. <h4>Methods</h4> We analyzed COMT variants in 2,251 PD patients and 2,835 controls of European descent using wh...

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Literature Corpus work: 82b8bc35-4eaa-560d-ba48-dd80a894d1c2
DOI: 10.1101/2025.04.11.25325572

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