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Article

BMP-2 and -4 produced by vascular smooth muscle cells from atherosclerotic lesions induce monocyte chemotaxis through direct BMPRII activation.

Atherosclerosis - 1 Jul 2014

Simões Sato Alex Yuri, Bub Guilherme Linhares, Campos Alexandre Holthausen

Abstract excerpt

OBJECTIVE: Monocytes and macrophages, together with vascular smooth muscle cells (VSMCs), play key roles at all stages of atherogenesis. There is also growing evidence that BMP signaling is involved in vascular diseases, including atherosclerosis. Here we evaluate the role played by the BMP agonist/antagonist axis in monocyte recruitment during atherogenesis. METHODS AND RESULTS: Using ApoE-/- mice and BMPs,...

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Identifiers

PMID: 24814649
DOI: 10.1016/j.atherosclerosis.2014.03.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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