Article
Molecular mechanisms mediating inflammation in vascular disease: special reference to monocyte chemoattractant protein-1.
Hypertension (Dallas, Tex. : 1979) - 1 Mar 2003
Egashira Kensuke
Abstract excerpt
There are several clinical challenges for the treatment of intractable cardiovascular diseases, including restenosis, atherosclerotic complications resulting from plaque rupture, severe tissue ischemia, and heart failure. Emerging evidence suggests that an inflammatory process is involved in the pathogenesis of such intractable diseases. In particular, inflammatory responses to arterial injury, which cause...
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