Article
Bmper inhibits endothelial expression of inflammatory adhesion molecules and protects against atherosclerosis.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2012
Pi Xinchun, Lockyer Pamela, Dyer Laura A, Schisler Jonathan C, Russell Brooke, Carey Stephen, Sweet Daniel Timothy, Chen Zhongming, Tzima Ellie, Willis Monte S, Homeister Jonathon W, Moser Martin, Patterson Cam
Abstract excerpt
OBJECTIVE: Bone morphogenetic proteins (Bmps) are important mediators of inflammation and atherosclerosis, though their mechanism of action is not fully understood. To better understand the contribution of the Bmp signaling pathway in vascular inflammation, we investigated the role of Bmper (Bmp endothelial cell precursor-derived regulator), an extracellular Bmp modulator, in an induced in vivo model of...
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