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Chemokines Control Mobilization, Recruitment, and Fate of Monocytes in Atherosclerosis

20 Mar 2015

Abstract excerpt

Atherosclerosis is a chronic inflammatory disease of large arteries and, among others, characterized by continuous influx of monocytes into the subendothelial space, subsequent macrophage accumulation, and foam cell formation. Chemokines and their receptors tightly orchestrate monocyte trafficking and fate from birth to death. This brief review summarizes our current understanding of the interplay between...

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PMID: 25792446
DOI: 10.1161/atvbaha.114.304649

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