Article
Common progenitor cells in mature B-cell malignancies: implications for therapy.
Current opinion in hematology - 1 Jul 2014
Green Michael R, Alizadeh Ash A
Abstract excerpt
PURPOSE OF REVIEW: This review summarizes the recent progress in defining the patterns of genetic evolution giving rise to relapse in follicular lymphoma and multiple myeloma, and discusses their implications with respect to 'personalized medicine'. RECENT FINDINGS: High-throughput sequencing studies have uncovered a large degree of clonal heterogeneity within tumors, and found that subclones have a variable...
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