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Article

The evolving contribution of hematopoietic progenitor cells to lymphomagenesis

7 Aug 2012

Abstract excerpt

Recent genomic studies have outlined a landscape of recurrent alterations within some subtypes of lymphoid cancer. Yet, the timing and cellular contexts during which these alterations occur (ie, the molecular ontogeny) remain poorly understood. Lymphoid malignancies offer an exceptional opportunity to delineate the ontogeny of somatic alterations, as lymphocyte differentiation absolutely requires the introduction...

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PMID: 22869790
DOI: 10.1182/blood-2012-05-414995

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