Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic dissection of the Drosophila melanogaster female head transcriptome reveals widespread allelic heterogeneity.

PLoS genetics - 1 May 2014

King Elizabeth G, Sanderson Brian J, McNeil Casey L, Long Anthony D, Macdonald Stuart J

Abstract excerpt

Modern genetic mapping is plagued by the "missing heritability" problem, which refers to the discordance between the estimated heritabilities of quantitative traits and the variance accounted for by mapped causative variants. One major potential explanation for the missing heritability is allelic heterogeneity, in which there are multiple causative variants at each causative gene with only a fraction having been...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Drosophila melanogaster

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Heterogeneity

Share to Quantitative Trait Loci

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 24810915
DOI: 10.1371/journal.pgen.1004322
PMCID: PMC4014434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic dissection of the Drosophila melanogaster female head transcriptome reveals widespread allelic heterogeneity.PMID 24810915Read ↗

Genomic variation and its impact on gene expression in Drosophila melanogaster.Semantic proximity Read ↗

Widespread Allelic Heterogeneity in Complex Traits.Semantic proximity Read ↗

Genetic variants regulating expression levels and isoform diversity during embryogenesis.Semantic proximity Read ↗

The road less traveled: from genotype to phenotype in flies and humans.Semantic proximity Read ↗

Saturating the eQTL map in <i>Drosophila melanogaster</i> : genome-wide patterns of cis and trans regulation of transcriptional variation in outbred populationsSemantic proximity Read ↗

Structural variants exhibit widespread allelic heterogeneity and shape variation in complex traits.Semantic proximity Read ↗

Barcoded Bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeastSemantic proximity Read ↗

Genetic dissection of a model complex trait using the Drosophila Synthetic Population Resource.Semantic proximity Read ↗

Gene expression networks in the Drosophila Genetic Reference Panel.Semantic proximity Read ↗

Diallel panel reveals a significant impact of low-frequency genetic variants on gene expression variation in yeast.Semantic proximity Read ↗

Barcoded bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast.Semantic proximity Read ↗

The Drosophila melanogaster Genetic Reference Panel.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.