Article

Barcoded Bulk QTL mapping reveals highly polygenic and epistatic architecture of complex traits in yeast

2021-09-09

Abstract excerpt

Mapping the genetic basis of complex traits is critical to uncovering the biological mechanisms that underlie disease and other phenotypes. Genome-wide association studies (GWAS) in humans and quantitative trait locus (QTL) mapping in model organisms can now explain much of the observed heritability in many traits, allowing us to predict phenotype from genotype. However, constraints on power due to statistical con...

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Literature Corpus work: 9c0f0b6a-ea8b-5257-a945-9c9c97dc0592
DOI: 10.1101/2021.09.08.459513

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