Article
The road less traveled: from genotype to phenotype in flies and humans.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2018
Anholt Robert R H, Mackay Trudy F C
Abstract excerpt
Understanding how genomic variation gives rise to phenotypic variation is essential for elucidating mechanisms of adaptive evolution, plant and animal breeding, and precision medicine. However, identifying causal links between DNA sequence variants and variation in phenotypes is challenging in human populations, due to large blocks of linkage disequilibrium in the genome and heterogeneous developmental histories,...
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