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Article

Genetic variants regulating expression levels and isoform diversity during embryogenesis.

Nature - 19 Jan 2017

Cannavò Enrico, Koelling Nils, Harnett Dermot, Garfield David, Casale Francesco P, Ciglar Lucia, Gustafson Hilary E, Viales Rebecca R, Marco-Ferreres Raquel, Degner Jacob F, Zhao Bingqing, Stegle Oliver, Birney Ewan, Furlong Eileen E M

Abstract excerpt

Embryonic development is driven by tightly regulated patterns of gene expression, despite extensive genetic variation among individuals. Studies of expression quantitative trait loci (eQTL) indicate that genetic variation frequently alters gene expression in cell-culture models and differentiated tissues. However, the extent and types of genetic variation impacting embryonic gene expression, and their...

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PMID: 28024300
DOI: 10.1038/nature20802

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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