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Article

Effect of the allelic variant of alcohol dehydrogenase ADH1B*2 on ethanol metabolism.

Alcoholism, clinical and experimental research - 1 Jun 2014

Kang Gaeun, Bae Kyung-Yeol, Kim Sung-Wan, Kim Jin, Shin Hee-Young, Kim Jae-Min, Shin Il-Seon, Yoon Jin-Sang, Kim Jong-Keun

Abstract excerpt

BACKGROUND: It has been known that ADH1B*2 allele has a protective effect against the development of alcohol dependence. However, the protection mechanism is still unknown. We investigated whether ADH1B gene polymorphism affects ethanol (EtOH) metabolism. METHODS: In a parent study, we conducted a randomized crossover trials on 24 healthy male subjects who were selected by genotyping: 12 with ALDH2*1/*1 (active...

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Source

Identifiers

PMID: 24797321
DOI: 10.1111/acer.12427

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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