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Article

Associations of ALDH2 and ADH1B genotypes with response to alcohol in Asian Americans.

Journal of studies on alcohol - 1 Mar 2005

Cook Travis A R, Luczak Susan E, Shea Shoshana H, Ehlers Cindy L, Carr Lucinda G, Wall Tamara L

Abstract excerpt

OBJECTIVE: Individuals with alcohol dependence are less likely to possess variant alleles of the alcohol-metabolizing genes, aldehyde dehydrogenase (ALDH2*2) and alcohol dehydrogenase (ADH1B*2), than non-alcohol-dependent controls. It is hypothesized that the mechanism through which these alleles protect against alcohol dependence is by causing elevations in acetaldehyde, which in turn cause an increased response...

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Source

Identifiers

PMID: 15957670
DOI: 10.15288/jsa.2005.66.196

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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