Article
IL17A and IL17F gene polymorphisms in patients with rheumatoid arthritis.
BMC musculoskeletal disorders - 11 May 2016
Pawlik Andrzej, Kotrych Daniel, Malinowski Damian, Dziedziejko Violetta, Czerewaty Michal, Safranow Krzysztof
Abstract excerpt
BACKGROUND: Interleukin-17 plays important role in the pathogenesis of rheumatoid arthritis (RA). The aim of this study was to examine the associations between polymorphisms in the IL17A and IL17F genes and RA. METHODS: We examined 422 RA patients and 337 subjects as a control group. Single nucleotide polymorphism (SNP) in the IL17A (rs2275913) and IL17F (rs763780, rs11465553, rs2397084) genes were genotyped...
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