Article
IL-17A and IL-17F genes variants and susceptibility to childhood asthma in Tunisia.
The Journal of asthma : official journal of the Association for the Care of Asthma - 1 May 2014
Maalmi Haifa, Beraies Anissa, Charad Rihab, Ammar Jamel, Hamzaoui Kamel, Hamzaoui Agnès
Abstract excerpt
OBJECTIVES: IL-17A and IL-17F are new pro-inflammatory cytokines implicated in neutrophilic inflammation and thus, involved in the pathogenesis of asthma. We investigated the possible association among asthma and IL-17A -197G/A (rs2275913), IL-17F 7488A/G (rs763780) and IL-17F 7383A/G (rs2397084). METHODS: The study was performed in 171 patients with asthma (mean age 9.5 years, 105 boys, and 66 girls) and 171...
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