Article
IL17A and IL17RA gene polymorphisms in Fanconi anemia.
Brazilian oral research - 1 Jan 2023
Mobile Rafael Zancan, Mendes Monalisa Castilho, Machado-Souza Cleber, Queiroz Priscila de Mattos, Bonfim Carmem Maria Sales, Torres-Pereira Cassius Carvalho, Schussel Juliana Lucena
Abstract excerpt
Fanconi anemia is a rare autosomal recessive disease. In this disease, cytokine pathways can induce the bone marrow failure that is observed in individuals with Fanconi anemia. Interleukin IL-17 exhibits a protective effect in organisms because it induces neutrophil recruitment and shows a pathological role in several models of autoimmune diseases, periodontal disease, cancer, allograft rejection, and graft...
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