Interleukin-17A and -17F genes polymorphisms in lung cancer.

doi:10.1016/j.cyto.2013.12.012

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Article

Interleukin-17A and -17F genes polymorphisms in lung cancer.

Cytokine - 1 Mar 2014

Kaabachi Wajih, ben Amor Amira, Kaabachi Safa, Rafrafi Ahlem, Tizaoui Kalthoum, Hamzaoui Kamel

Abstract excerpt

Interleukin-17 (IL-17) is a proinflammatory cytokines produced by T helper 17 (Th17) cells, which plays an important role in both innate and adaptive immune systems. Genetic variants in the IL-17 genes may influence the immunopathogenesis of many cancers. In our study, we investigated the association of three single-nucleotide polymorphisms (SNPs: -152 G/A, 7488 A/G and 7383 A/G) in the IL-17A and IL-17F genes...

Topics

Adult
Aged
Aged, 80 and over
Case-Control Studies
Female
Gene Frequency
Gene-Environment Interaction
Genetic Predisposition to Disease
Haplotypes
Humans
Interleukin-17

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lung Neoplasms

Male

Middle Aged

Neoplasm Metastasis

Polymorphism, Restriction Fragment Length

Polymorphism, Single Nucleotide

Risk Factors

Source

Open in PubMed

Identifiers

PMID: 24548421
DOI: 10.1016/j.cyto.2013.12.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24548421-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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