Article
Interleukin-17A and -17F genes polymorphisms in lung cancer.
Cytokine - 1 Mar 2014
Kaabachi Wajih, ben Amor Amira, Kaabachi Safa, Rafrafi Ahlem, Tizaoui Kalthoum, Hamzaoui Kamel
Abstract excerpt
Interleukin-17 (IL-17) is a proinflammatory cytokines produced by T helper 17 (Th17) cells, which plays an important role in both innate and adaptive immune systems. Genetic variants in the IL-17 genes may influence the immunopathogenesis of many cancers. In our study, we investigated the association of three single-nucleotide polymorphisms (SNPs: -152 G/A, 7488 A/G and 7383 A/G) in the IL-17A and IL-17F genes...
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