Article
Mitochondrial DNA polymorphisms associated with longevity in the Turkish population.
Mitochondrion - 1 Jul 2014
Guney Ozgur, Ak Handan, Atay Sevcan, Ozkaya Ali Burak, Aydin Hikmet Hakan
Abstract excerpt
The accumulation of mutations in mitochondrial DNA is a widely recognized mechanism for aging and age related diseases. However, studies indicate that some mutations could be beneficial to longevity by slowing down the function of the electron transport chain, reducing free radical production. In this study, we re-sequenced the entire mitochondrial DNA from 50 individuals and examined aging-related variations in...
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