Article
Mitochondrial DNA alterations in aging.
Annals of the New York Academy of Sciences - 1 Apr 2007
Oztürk Kamile, Olgun Abdullah, Saruhan Ercan, Ergen Aydan, Akman Serif, Erbil M Kemal
Abstract excerpt
During the aging process, the increase of mitochondrial DNA (mtDNA) alterations has been reported. In this study, we investigated deletions/insertions in the approximately 2.4-kb region (from 14680 to 578 bp) of mtDNA covering D-loop region. A total of 96 individuals (ages between 20 and 94 years) were screened in this study. Genomic DNA was purified from whole blood samples. The 2.4-kb region of mtDNA was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
