Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics.

BMC genomics - 29 Apr 2014

Yang Hsin-Chou, Lin Chien-Wei, Chen Chia-Wei, Chen James J

Abstract excerpt

BACKGROUND: Gene-based analysis has become popular in genomic research because of its appealing biological and statistical properties compared with those of a single-locus analysis. However, only a few, if any, studies have discussed a mapping of expression quantitative trait loci (eQTL) in a gene-based framework. Neither study has discussed ancestry-informative eQTL nor investigated their roles in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to TAP2 gene
Share to Genome
Share to Pharmacogenetics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 24779372
DOI: 10.1186/1471-2164-15-319
PMCID: PMC4236814

Genes

KIF6
SPG7
TAP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics.PMID 24779372Read ↗

Expression quantitative trait loci (eQTL): from population genetics to precision medicine.Semantic proximity Read ↗

On Using Local Ancestry to Characterize the Genetic Architecture of Human Phenotypes: Genetic Regulation of Gene Expression in Multiethnic or Admixed Populations as a ModelSemantic proximity Read ↗

Powerful mapping of<i>cis</i>-genetic effects on gene expression across diverse populations reveals novel disease-critical genesSemantic proximity Read ↗

Importance of genetic ancestry in pharmacogenomics for precision medicine.Semantic proximity Read ↗

Genetic ancestry plays a central role in population pharmacogenomics.Semantic proximity Read ↗

Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture.Semantic proximity Read ↗

Multi-ancestry gene expression models amplify transcriptome-wide association study discovery and validation.Semantic proximity Read ↗

Local ancestry modulates gene expression: shifting our understanding of genetic regulation and disease association within and across populationsSemantic proximity Read ↗

Peripheral Blood Nascent RNA Sequencing Captures Ancestry-Linked Differential Gene ExpressionSemantic proximity Read ↗

Integrative Mapping of Regulatory Variation in African American Hepatocytes Using Colocalization and MPRA: Toward Precision Drug ResponseSemantic proximity Read ↗

MATS: a novel multi-ancestry transcriptome-wide association study to account for heterogeneity in the effects of cis-regulated gene expression on complex traits.Semantic proximity Read ↗

Clinical and Therapeutic Applications of Individual-level Tissue-Specific Imputed TranscriptomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.