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Article

Importance of genetic ancestry in pharmacogenomics for precision medicine.

Pharmacogenomics - 1 Jan 2025

Venkatesh Rasika, Keat Karl, Salvatore Maxwell, Cindi Zinhle, Hall Molly A, Ritchie Marylyn D

Abstract excerpt

Genetic ancestry refers to an individual's biogeographical origins inferred from correlated allele frequencies shared with individuals from similar ancestral regions. Understanding the complexities of genetic ancestry has proven beneficial in the field of pharmacogenomics (PGx), where personalized medication regimens are optimizing therapeutic outcomes while minimizing the risk of side effects. With the rise in...

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PMID: 41652975
DOI: 10.1080/14622416.2026.2620360
PMCID: PMC12915776

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