Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic ancestry plays a central role in population pharmacogenomics.

Communications biology - 5 Feb 2021

Yang Hsin-Chou, Chen Chia-Wei, Lin Yu-Ting, Chu Shih-Kai

Abstract excerpt

Recent studies have pointed out the essential role of genetic ancestry in population pharmacogenetics. In this study, we analyzed the whole-genome sequencing data from The 1000 Genomes Project (Phase 3) and the pharmacogenetic information from Drug Bank, PharmGKB, PharmaADME, and Biotransformation. Here we show that ancestry-informative markers are enriched in pharmacogenetic loci, suggesting that trans-ancestry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Pharmacological
Share to Biotransformation
Share to Gene-Environment Interaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inactivation, Metabolic

Share to Precision Medicine

Share to Principal Component Analysis

Share to Proteome

Share to Racial Groups

Source

Open in PubMed Open full text

Identifiers

PMID: 33547344
DOI: 10.1038/s42003-021-01681-6
PMCID: PMC7864978

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic ancestry plays a central role in population pharmacogenomics.PMID 33547344Read ↗

Importance of genetic ancestry in pharmacogenomics for precision medicine.Semantic proximity Read ↗

Genetic Ancestry Inference for Pharmacogenomics.Semantic proximity Read ↗

Application of principal component analysis to pharmacogenomic studies in Canada.Semantic proximity Read ↗

Ancestry Composition: A Novel, Efficient Pipeline for Ancestry DeconvolutionSemantic proximity Read ↗

European population genetic substructure: further definition of ancestry informative markers for distinguishing among diverse European ethnic groups.Semantic proximity Read ↗

Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics.Semantic proximity Read ↗

Developing a novel panel of genome-wide ancestry informative markers for bio-geographical ancestry estimates.Semantic proximity Read ↗

Predicting the genetic ancestry of 2.6 million New York City patients using clinical dataSemantic proximity Read ↗

Using the UK Biobank as a global reference of worldwide populations: application to measuring ancestry diversity from GWAS summary statistics.Semantic proximity Read ↗

AncestrySNPminer: a bioinformatics tool to retrieve and develop ancestry informative SNP panels.Semantic proximity Read ↗

A scalable pipeline for local ancestry inference using tens of thousands of reference haplotypesSemantic proximity Read ↗

Studying the Genetics of Complex Disease With Ancestry-Specific Human Phenotype Networks: The Case of Type 2 Diabetes in East Asian Populations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.