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Powerful mapping of<i>cis</i>-genetic effects on gene expression across diverse populations reveals novel disease-critical genes

2024-09-26

Abstract excerpt

While disease-associated variants identified by genome-wide association studies (GWAS) most likely regulate gene expression levels, linking variants to target genes is critical to determining the functional mechanisms of these variants. Genetic effects on gene expression have been extensively characterized by expression quantitative trait loci (eQTL) studies, yet data from non-European populations is limited. This...

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Literature Corpus work
c0450342-5290-5b75-82aa-99a669167127
DOI
10.1101/2024.09.25.24314410
Open publication

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Powerful mapping of<i>cis</i>-genetic effects on gene expression across diverse populations reveals novel disease-critical genesDOI 10.1101/2024.09.25.24314410
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