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Article

Prdm9 incompatibility controls oligospermia and delayed fertility but no selfish transmission in mouse intersubspecific hybrids.

PloS one - 1 Jan 2014

Flachs Petr, Bhattacharyya Tanmoy, Mihola Ondřej, Piálek Jaroslav, Forejt Jiří, Trachtulec Zdenek

Abstract excerpt

PR-domain 9 (Prdm9) is the first hybrid sterility gene identified in mammals. The incompatibility between Prdm9 from Mus musculus domesticus (Mmd; the B6 strain) and the Hstx2 region of chromosome (Chr) X from M. m. musculus (Mmm; the PWD strain) participates in the complete meiotic arrest of mouse intersubspecific (PWD×B6)F1 hybrid males. Other studies suggest that also semisterile intersubspecific hybrids are...

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Identifiers

PMID: 24756080
DOI: 10.1371/journal.pone.0095806
PMCID: PMC3995920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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