Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions.

doi:10.7554/eLife.02504

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Genome-wide mapping in a house mouse hybrid zone reveals hybrid sterility loci and Dobzhansky-Muller interactions.

eLife - 9 Dec 2014

Turner Leslie M, Harr Bettina

Abstract excerpt

Mapping hybrid defects in contact zones between incipient species can identify genomic regions contributing to reproductive isolation and reveal genetic mechanisms of speciation. The house mouse features a rare combination of sophisticated genetic tools and natural hybrid zones between subspecies. Male hybrids often show reduced fertility, a common reproductive barrier between incipient species. Laboratory...

Topics

Animals
Chromosome Mapping
Computer Simulation
Epistasis, Genetic
Genome
Genome-Wide Association Study
Hybridization, Genetic
Infertility, Male
Male
Mice
Models, Genetic
Organ Size
Phenotype
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Testis

Source

Open in PubMed Open full text

Identifiers

PMID: 25487987
DOI: 10.7554/eLife.02504
PMCID: PMC4359376

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics