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Article

Association of CHMP4B and Autophagy with Micronuclei: Implications for Cataract Formation

1 Jan 2014

Abstract excerpt

Autophagy is a mechanism of cellular self-degradation that is very important for cellular homeostasis and differentiation. Components of the endosomal sorting complex required for transport (ESCRT) machinery are required for endosomal sorting and also for autophagy and the completion of cytokinesis. Here we show that the ESCRT-III subunit CHMP4B not only localizes to normal cytokinetic bridges but also to...

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Identifiers

PMID: 24741567
DOI: 10.1155/2014/974393

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