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Article

Immunohistochemical analysis of PDK1 expression in breast cancer.

Diagnostic pathology - 16 Apr 2014

Arsenic Ruza

Abstract excerpt

BACKGROUND: 3-phosphoinositide-dependent protein kinase-1 (PDK1) functions downstream of phosphoinositide 3-kinase (PIK3) and activates members of the AGC family of protein kinases that are known to play crucial roles in physiological processes associated with cell metabolism, growth, proliferation and survival. Changes in the expression and activity of PDK1 and several AGC kinases have been linked to human...

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Source

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Identifiers

PMID: 24739482
DOI: 10.1186/1746-1596-9-82
PMCID: PMC4005628

Genes

PDK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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