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Article

Elevated phosphorylation and activation of PDK-1/AKT pathway in human breast cancer.

British journal of cancer - 12 Dec 2005

Lin H-J, Hsieh F-C, Song H, Lin J

Abstract excerpt

Activation of kinases signalling pathways contributes to various malignant phenotypes in human cancers, including breast tumour. To examine the possible activation of these signalling molecules, we examined the phosphorylation status in 12 protein kinases and transcription factors in normal primary human mammary epithelial cells, telomerase-immortalised human breast epithelial cell line, and two breast cancer...

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Share to 3-Phosphoinositide-Dependent Protein Kinases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16288304
DOI: 10.1038/sj.bjc.6602862
PMCID: PMC2361529

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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