Article
[Clinical, diagnostic significance and theranostic interest of PIK3CA gene mutations in breast cancer].
Bulletin du cancer - 1 Oct 2013
Harlé Alexandre, Lion Maëva, Lozano Nicolas, Merlin Jean-Louis
Abstract excerpt
Breast cancer is the most common cancer among women with more than 53,000 new cases every year in France. The PI3K/AKT pathway is one of the major pathways involved in mammary tumorigenesis. The first effector of this pathway downstream Human Epidermal growth factor Receptor (HER receptors) is th...
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