Article
A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation and better prognosis of gastric cancer.
Journal of cancer research and clinical oncology - 1 Aug 2014
Wang Xiaoting, Lin Youdong, Lan Fenghua, Yu Yinghao, Ouyang Xuenong, Wang Xuzhou, Huang Qiaojia, Wang Lie, Tan Jianming, Zheng Feng
Abstract excerpt
PURPOSE: v-akt Murine thymoma viral oncogene homolog (AKT) pathway is critically involved in cancer cell growth, invasion, and survival. We examined the correlation between the genetic variations in molecules of AKT pathway and clinical outcomes of gastric cancer. PATIENTS AND METHODS: Six single...
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