Article
Mice with altered brain lipoprotein metabolism display maladaptive responses to environmental challenges that may predispose to weight gain.
Metabolic syndrome and related disorders - 1 Aug 2014
Pellinen Jacob, Wang Hong, Eckel Robert H
Abstract excerpt
BACKGROUND: Three-month-old neuron-specific lipoprotein lipase (LPL)-depleted mice (NEXLP(-/-)) mice are preobese and have normal body weight before developing obesity by 4.5 months. This series of experiments investigated responses to novel environment stimuli and acute sleep deprivation in preo...
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